单身男子大卫(马克·鲁弗洛 Mark Ruffalo饰)为了忘掉伤心事,决定出租自己的公寓。怪事开始发生:一个叫伊丽莎白(瑞茜·威瑟斯彭 Reese Witherspoon饰)的姑娘闯入了大卫的生活,声称这是她的房子。 伊丽莎白似乎拥有超乎凡人的能力,她能随时出现在各个处所,纠缠大卫逼他搬走。然而,她却不知道这背后隐藏着一个残酷的事实——其实伊丽莎白只是一具鬼魂。她生前是一个工作狂,在一场车祸中遇难。大卫请来驱鬼人,伊丽莎白渐渐知晓自己的身份。在这个过程中,大卫和伊丽莎白之间产生了人鬼之恋,伊丽莎白生前和大卫一段错过的缘分,伴随着这段无果的恋情显得倍加唏嘘。Elizabeth Masterson, a dedicated doctor in San Francisco, had almost no time for anything. When her sister with two kids set her up on a date, she gets into a tragic car crash and goes into a coma. Meanwhile, a landscape architect named David Abbott moves to San Francisco and, coincidentally, into Elizabeth's apartment for rent. While at the apartment, Elizabeth's spirit haunts him. She doesn't remember who she is, who her family is or what she did - All that she remembered was her apartment and where everything was. To settle the arguments, David agrees to figure out who Elizabeth really is. When they get close to figuring out who she is, they eventually find love with one another and as they finally know who she really is, they learn that fate really has put them both together.