在这部续集中,生产机械战警的泛消费公司掌控着底特律城的治安,警察们因薪水迟迟不能到位而举行罢工。凯恩(Tom Noonan 饰)旗下的犯罪集团依靠制造风靡各地的毒品“纽克”大发横财,社会治安极度败坏,到处是暴力事件。机械警察墨菲(Peter Weller 饰)追查毒品,将凯恩的制毒工厂捣毁,由此被凯恩团伙埋伏,惨遭肢解。与此同时,泛消费公司趁市政府财务困难,凭合同欲将城市行政纳入公司范畴,泛消费的新机械战警开发计划屡屡失败,于是请到心理学家菲克斯参与设计,菲克斯改动墨菲的命令程序使其无法如常工作,从错误程序摆脱出来的墨菲带领一干热血干警横扫凯恩总部,但是菲克斯却将凯恩改造成为巨大的机械战警,墨菲与凯恩的再次战斗不可避免……After a successful deployment of the Robocop Law Enforcement unit, OCP sees its goal of urban pacification come closer and closer, but as this develops, a new narcotic known as "Nuke" invades the streets led by God-delirious leader Cane. As this menace grows, it may prove to be too much for Murphy to handle. OCP tries to replicate the success of the first unit, but ends up with failed prototypes with suicidal issues... until Dr. Faxx, a scientist straying away from OCP's path, uses Cane as the new subject for the Robocop 2 project, a living God.