昏暗的霓虹灯下,阴冷潮湿的城市里栖息着两名神秘女子:克拉拉(杰玛·阿特登 Gemma Arterton 饰)和埃莉诺(西尔莎·罗南 Saoirse Ronan 饰)。她们以姐妹相称,固守着在都市一隅的方寸空间,不愿引起他人的注意。对于血族来说,这也许是最好的办法。只是在 命运的驱赶下,“安宁”注定与她们无缘,两人辗转来到了另一座城市。四处寻找生计的克拉拉偶然结识刚刚失去母亲的中年男子诺埃尔(丹尼尔·梅斯 Daniel Mays 饰),相似的境遇让他们感同身受。诺埃尔因此为这两名美丽女子提供栖身之所。 绵亘上百年的凄惶记忆,无以排遣的永生孤独,以及深锁心底的秘密,随着鲜红的血液缓缓流淌……Two mysterious women seek refuge in a run-down coastal resort. Clara meets lonely Noel, who provides shelter in his deserted guesthouse, Byzantium. Schoolgirl Eleanor befriends Frank and tells him their lethal secret. They were born 200 years ago and survive on human blood. As knowledge of their secret spreads, their past catches up on them with deathly consequence.